Table 1 Recent studies on the role of Piezo1 in skeletal muscle

Hirano et al. [21]

Satellite cell regeneration

PIEZO1 promotes proliferation and regenerative functions of MuSCs through precise control of cell division.

Ma et al. [9]

Morphologies of satellite cell

Satellite cells were classified into three functionally distinct stem cell states: responsive, intermediate, and sensory. Yoda1 treatment promoted an increased percentage of responsive satellite cells.

Quiroga et al. [22]

Myogenic differentiation

Short-term treatment with Yoda1 significantly enhanced cell fusion

Peng et al. [23]

Satellite cell activation

Piezo1 represses activation, leading to fewer satellite cell via cell senescence.

Hirata et al. [34]

Muscle atrophy

Acute disruption of Piezo1 in skeletal muscle induced Klf15 and Il6 expression as well as muscle atrophy.