Fig. 7
Histopathological evaluation of left and right ventricles. A H&E on heart sections from WT, DMD vehicle and DMD treated with FSK by IP or SC administration. Scale bar 600 μm. B SR staining on heart sections from WT, DMD vehicle and DMD treated with FSK by IP or SC administration. Scale bar 600 μm. C Quantification of the histopathological index. D Quantification of fibrosis and SR positive area. E ECG evaluation of QTpc value that corresponds to the interval from the Q wave to the peak of the T wave (QTp) corrected with the Bazette’s formula normalized to the average rat RR (QTpc = QTp(eak) / (RR / f)1/2, f = 150 ms)