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Fig. 5 | Skeletal Muscle

Fig. 5

From: ActRII or BMPR ligands inhibit skeletal myoblast differentiation, and BMPs promote heterotopic ossification in skeletal muscles in mice

Fig. 5

Local AAV delivery of BMP7 and BMP9 promotes heterotopic ossification in mouse skeletal muscle. (A) H&E staining of tibialis anterior (TA) cross-sections from mice 1-month post-intramuscular AAV delivery. Representative images of n = 2 mice per group are shown, each at 4X, 10X, and 20X magnification (total numbers of mice were, n = 11 for AAV: BMP7 and n = 12 for AAV1: control or AAV1:BMP9). Boxes indicate select corresponding magnified areas. Arrows indicate areas of ossification. (B) Images of dissected lower limbs from mice1-month post-intramuscular AAV delivery. Representative images of n = 2 mice per group are shown. Arrows indicate areas of ossification

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Skeletal Muscle

ISSN: 2044-5040

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