Skip to main content
Fig. 2 | Skeletal Muscle

Fig. 2

From: Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice

Fig. 2

AGH treatment restored autophagy in mdx mice. TA muscles from WT, mdx, and AGH-treatment mdx mice were isolated at 8 weeks of age. Representative immunofluorescence images and quantifications for (A–B) LC3 (arrows representing autophagosomes), (C–D) p62, (E–F) Pink1 (red), wheat germ agglutinin (WGA, green), and DAPI (blue, 20× magnification, scale bar = 100 μm). Quantification of fluorescence intensities using ImageJ software. Values are presented as the mean ± standard error of the mean for each experiment (n = 5). * p < 0.05 compared with WT control, # p < 0.05 compared with mdx

Back to article page

Skeletal Muscle

ISSN: 2044-5040

Contact us