Fig. 2

Reduced force generation in regenerated TA muscles lacking Wnt7a. (A) Schematic of mouse strains used and experimental design. (B) Specific force frequency curve in uninjured WT TA muscle with (dark blue) and without (light blue) Wnt7a expression. (C) Specific force frequency curve in uninjured mdx TA muscle with (dark green) and without (light green) Wnt7a expression. (D) Specific force frequency curve of regenerated WT TA muscle, with (dark blue) and without (light blue) Wnt7a expression, at 21 d following injury. (E) Specific force frequency curve of regenerated mdx TA muscle, with (dark green) and without (light green) Wnt7a expression, at 21 d following injury. TA (Tibialis Anterior). n\(\:\ge\:\)3 mice, mean ± s.e.m., p values determined by two-way ANOVA test (*p<0.05, **p < 0.01, ***p < 0.001, n.s.=not significant)