Fig. 2

Fatty infiltration of GM, RF, TFL and VL in affected limb of HOA patients. a Representative images of haematoxylin and eosin (H&E)-stained sections. Yellow arrowheads indicate intramuscular adipocytes. Scale bars, 1000 µm; scale bars in the inserts, 50 µm. b Relative adipocyte area in the biopsies. c Repeated-measures correlation between the relative fatty infiltrated area assessed with MRI and the relative adipocyte content assessed with H&E staining in the skeletal muscle biopsies. Values from each patient are displayed in one color, with corresponding lines to show the repeated-measures correlation fit for each patient. Data presented as mean and standard deviation (b). Data were analyzed using repeated-measures one-way ANOVA and Dunnett’s post-hoc test (b), or repeated-measures correlation (c). * p < 0.05, ** p < 0.005, *** p < 0.0005 compared to the GM. GM, gluteus minimus; HOA, hip osteoarthritis; RF, rectus femoris; TFL, tensor fascia latae; VL vastus lateralis