Fig. 4

Acomys and Mus display similar injury responses to VML trough injury. A Model diagram of TA trough injury. B Mean % muscle removed by wet mass of Mus and Acomys TA muscles following trough injuries (error bars ± SD: *, p < 0.05, Student’s t-test). n = 9 Mus, n = 7 Acomys. C, D Mean TA weights 90 DPI in (C) Mus and (D) Acomys (error bars ± SEM: *, p < 0.05, Student’s t-test). E H&E and picrosirius red stained cross-sections of Mus and Acomys TA muscles 90 days post VML trough injury. Scale bar = 400 μM. F Total number of myofibers per TA cross-Sect. 90 DPI in Mus and Acomys (error bars ± SEM: *, p < 0.05, 2-way ANOVA). G, H Myofiber size distribution by MinFeret diameter 90 DPI in (G) Mus and (H) Acomys (error bars ± SEM)