Fig. 1

Modeling VML injuries across species. A Body weight (g) differences between male and female C57BL6/J Mus and Acomys (error bars ± SEM: *, p < 0.05, Student’s t-test). n = 20 male Mus, n = 17 female Mus, n = 13 male Acomys, n = 11 female Acomys. B TA weight (mg) differences between male and female C57BL6/J Mus and Acomys (error bars ± SEM: *, p < 0.05, Student’s t-test). C Total number of myofibers per TA cross-section in Mus and Acomys (error bars ± SEM: *, p < 0.05, Student’s t-test). n = 12 Mus, n = 9 Acomys. D Average MinFeret diameter of myofibers per TA cross-section in Mus and Acomys (error bars ± SEM: *, p < 0.05, Student’s t-test). n = 12 Mus, n = 9 Acomys. E Myofiber size distribution by MinFeret diameter in Mus and Acomys (error bars ± SEM). Bars are overlapping. F Model diagram of biopsy punch injury in TA. G Mean % muscle removed by wet mass of Mus and Acomys TA muscles using indicated biopsy punch sizes (error bars ± SD: *, p < 0.05, One-way ANOVA with Tukey’s multiple comparisons test)