Fig. 4

Myofiber size and types in running HeyL-KO mice. (A) Representative images of staining for Type-IIa (plantaris), Type-IIb (plantaris), and Type-I (soleus) with anti-laminin staining (green) in male WT or KO mice. Scale bar: 100 μm. (B) Cross sectional area (CSA) of Type-IIa or -IIb myofibers in plantaris muscle (PLA) from male WT (-Ex; n = 5, +Ex; n = 5) or KO (-Ex; n = 5, +Ex; n = 4) mice. (C) The frequency of Type-IIa or -IIb myofibers in plantaris (PLA) muscle from male WT (-Ex; n = 5, +Ex; n = 5) or KO (-Ex; n = 5, +Ex; n = 4) mice. (D) CSA of Type-I or -IIa myofibers in soleus muscle from male WT (-Ex; n = 5, +Ex; n = 5) or KO (-Ex; n = 5, +Ex; n = 4) mice. (E) The frequency of Type-I or -IIa myofibers in soleus muscle from male WT (-Ex; n = 5, +Ex; n = 5) or KO (-Ex; n = 5, +Ex; n = 4) mice