Fig. 3

Muscle response to exercise in HeyL-KO mice. (A) Experimental scheme for analyzing the effect of 4-week wheel running on muscle weight and myofiber types. Littermate male control (WT: HeyL+/+) or HeyL-KO (KO: HeyL−/−) mice were randomly separated into two groups; home cage (-Ex: non-exercise group) or wheel running cage (+ Ex: exercise group). (B) Number of wheel rotations during 4 weeks in WT (n = 5) or KO (n = 4) mice.(C) Normalized muscle weight [muscle weight/body weight (BW)] from WT or KO mice. N.S.: not significant