Fig. 5

Heart failure reduces muscle function. Muscle function was measured with a grip strength meter for the forelimbs and four limbs (forelimb and hindlimbs) of mice subjected to sham and transverse aortic constriction surgeries for 14 weeks. (A) Forelimb muscle strength and (B) total muscle strength (forelimb and hind limb) muscle strength. Data are presented as the mean ± SEM; n = 9–10 samples in each group; *p = 0.0001 vs sham