Fig. 2

Transverse aortic constriction (TAC)-induced heart failure decreases muscle weight. C57BL/6J mice were subjected to sham and TAC surgeries for 14 weeks. (A) Weights of the gastrocnemius (gastroc) muscle, (B) soleus muscle, (C) tibialis anterior muscle, and (D) extensor digitorium longus (EDL) muscle were normalized to tibia length. Data are presented as the mean ± SEM, n = 10 samples in each group, *p < 0.05 vs sham