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Fig. 7 | Skeletal Muscle

Fig. 7

From: Muscle degeneration in aging Drosophila flies: the role of mechanical stress

Fig. 7

Muscle degeneration is increased in bang-sensitive flies. A TDT muscles from flies with jus knockdown in the nervous system (jus KDNEU, elav > jus KD, pale green) and their isogenic control (CNTRNEU, elav/ + , dark green) aged for 4 weeks at 29 °C. B Jump test results. The jus KDNEU flies have fully functional TDTs. C, D TDT degeneration scores in flies of various genotypes and treatments. “Stimulus” denotes daily vigorous shaking for 10 s to invoke the bang response; jus KDMUS is jus knockdown in muscles (Mef2 > jus KD, light blue) and their control (CNTRMUS, Mef2/ + , dark blue), FH Quantification of fiber degeneration in subalar muscles from the same flies and under the same conditions as in panels C, D. Statistical significance by Fisher’s exact test: (*) p < 0.05. Scale bars: 50 µm

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