Fig. 3
From: Skeletal muscle vulnerability in a child with Pitt-Hopkins syndrome
Immunofluorescence-based studies of myofibroblasts on TCF4-mutant muscle. Reduced co-localization of CD90 and Vimentin in the muscle biopsy specimen of the PTHS patient compared to sex- and age-matched normal disease controls (NDC). Nuclei are visualized by DAPI staining. Co-localization is indicated by yellow arrows whereas areas solely immunoreactive for Vimentin are highlighted with green arrows. Scale bars: 50 µm