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Fig. 5 | Skeletal Muscle

Fig. 5

From: ASM is a therapeutic target in dermatomyositis by regulating the differentiation of naive CD4 + T cells into Th17 and Treg subsets

Fig. 5

AMI regulates the CD4 + T cells differentiation in EAM mouse model. (A) mRNA expression level of RORγT in muscle tissues detected by qRT-PCR (B) mRNA expression level of RORγT in spleen detected by qRT-PCR (C) mRNA expression level of FOXP3 in muscle tissues detected by qRT-PCR (D) mRNA expression level of FOXP3 in spleen detected by qRT-PCR. (E) protein level of p-STAT3 and STAT3 in muscle tissue detected by WB (F) the quantitative anaysis of p-STAT3/STAT3 (G) protein level of p-STAT5 and STAT5 in muscle tissue detected by WB (H) the quantitative anaysis of p-STAT5/STAT5. *P < 0.05, **P < 0.01. ***P < 0.001, n ranges from 4 to 7 in each analysis group

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