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Fig. 2 | Skeletal Muscle

Fig. 2

From: ASM is a therapeutic target in dermatomyositis by regulating the differentiation of naive CD4 + T cells into Th17 and Treg subsets

Fig. 2

ASM plays a crucial role in the pathology of EAM mice. Establishment of EAM mouse model in ASM knockout (SMPD1−/−) mice. (A) muscle strength (B) serum CK level (C) spleen (D) spleen weight (E) H&E staining of muscle section (F) quantitative analysis of H&E staining. *P < 0.05, ** P < 0.01, *** P < 0.001, n = 6 in SMPD1+/+ mice group, n = 5 SMPD1−/− mice group

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