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Fig. 1 | Skeletal Muscle

Fig. 1

From: ASM is a therapeutic target in dermatomyositis by regulating the differentiation of naive CD4 + T cells into Th17 and Treg subsets

Fig. 1

ASM exhibits high expression in DM patients and associates with disease activity. (A) serum ASM levels detected using ELISA (B) mRNA expression level of ASM in muscle tissues of patients (C) protein levels of ASM in patients’ muscle tissues, scale bar 20 μm (D) serum ASM activity (E) Correlation analysis between serum ASM levels and overall disease activity (F) Correlation analysis between serum ASM levels and cutaneous severity score. *P < 0.05, **P < 0.01, ***P < 0.001, n = 30 in healthy controls, n = 58 in patients with DM

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