Fig. 6
HMOX1 induction in SCs attenuates skeletal muscle necrotic events upon physical exercise. A-E Necrosis assessment in tibialis anterior (TA), gastrocnemius (GAS) and diaphragmae (DIA) tissue sections of mdx and mdx;HMOX1Pax7Ind mice. (A) Representative scans of TA. Scale bar: 500 μm. B Representative images of necrotic events in TA, DIA and GAS. Scale bar: 100 μm. Semiquantitative analysis in (C) TA, (D) GAS and (E) DIA. Immunofluorescent staining of IgG and IgM (green) (n = 3–8). Data is presented as mean± SEM. # p < 0.05—Two-way ANOVA variation; * p < 0.05 by Two-way ANOVA with Tukey’s post hoc test