Fig. 5

HMOX1 induction in SCs modulates skeletal muscle inflammation in dystrophic mice. A-E Inflammation assessment in tibialis anterior (TA), diaphragmae (DIA) and gastrocnemius (GAS) tissue sections. (A) Representative images of leukocyte infiltration/necrosis in skeletal muscles. Scale bar: 100 μm. B-D Semiquantitative analysis in (B) TA, (C) GAS and (D) DIA (n = 5–9). H&E staining. Relative expression of Il10 in TA. qPCR (n = 3–7). Data is presented as mean± SEM. # p < 0.05, ## p < 0.05—Two-way ANOVA variation; ** p < 0.01 by Two-way ANOVA with Tukey’s post hoc test