Fig. 6

Motor neuron density and soma size are unaffected by Megf10 KO. (A) Representative images of neurons labeled with NeuN (cyan) and cholinergic synapses stained against VAChT (magenta) in cross sections of the ventral horn of the lumbar spinal cord from young adult (3 mo) male WT and Megf10 KO mice. Alpha motor neurons are identified as large NeuN + cells with cholinergic synapses along their soma and dendrites. Motor neuron (B) density and (C) soma size (cross sectional area (CSA)) are unaffected in Megf10 KO mice. Unpaired 2-sided Student’s t-test for statistical analysis. Values represented as mean + SD.