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Fig. 5 | Skeletal Muscle

Fig. 5

From: Eldecalcitol prevents muscle loss and osteoporosis in disuse muscle atrophy via NF-κB signaling in mice

Fig. 5

Effects of eldecalcitol on myotube atrophy induced by TNF-α in a concentration-dependent manner. a–d Western blotting indicated that 10 nM eldecalcitol repressed muscle atrophy caused by 100 ng/ml TNF-α in C2C12 myotubes. e–f Immunofluorescence showed that 10 nM eldecalcitol increased myotube diameter. Values are presented as mean ± SEM, n ≥ 3. *P < 0.05; **P < 0.01; ***P < 0.001 vs. Con group; #P < 0.05; ##P < 0.01; ###P < 0.001 vs TNF-α group. Con, control; ELD, eldecalcitol; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; SEM, standard error of mean

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Skeletal Muscle

ISSN: 2044-5040

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