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Fig. 8 | Skeletal Muscle

Fig. 8

From: Multi-omics analysis of sarcospan overexpression in mdx skeletal muscle reveals compensatory remodeling of cytoskeleton-matrix interactions that promote mechanotransduction pathways

Fig. 8

SSPN overexpression rewires ECM-cell communication. Schematic summarizing ECM and cytoskeletal changes in RNA sequencing and proteomic data sets. Changes in gene or protein expression are represented by color according to the key, indicating compensatory upregulation of many ECM and cytoskeletal molecules with downstream signaling effects (in purple). The x- and y-axes in the color key correspond to mdxTG relative to WT and mdxTG relative to mdx, respectively

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Skeletal Muscle

ISSN: 2044-5040

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