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Fig. 5 | Skeletal Muscle

Fig. 5

From: Multi-omics analysis of sarcospan overexpression in mdx skeletal muscle reveals compensatory remodeling of cytoskeleton-matrix interactions that promote mechanotransduction pathways

Fig. 5

Activated and inhibited upstream regulators identified in wild-type, mdx and mdxTG muscle through ingenuity pathway analysis. Ingenuity pathway analysis (IPA) of RNA sequencing data (a) and mass spectrometry data (b) identifying the top 10 upstream regulators that are activated (z-score, red bars) or inhibited (z-score, blue bars) with −log p-values overlaid in black. Comparisons include WT vs mdx (left graphs), WT vs mdxTG (middle graphs), and mdx vs mdxTG (right graphs)

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Skeletal Muscle

ISSN: 2044-5040

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