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Fig. 7 | Skeletal Muscle

Fig. 7

From: Effect of chronic intermittent hypoxia (CIH) on neuromuscular junctions and mitochondria in slow- and fast-twitch skeletal muscles of mice—the role of iNOS

Fig. 7

Representative TEM images of WT (A, B) and iNOS−/− (C, D) soleus muscle under CIH (B, D) vs. NOX (A, C) (scale bars = 100 nm). Percentage of damaged (E) and swollen mitochondria (F) are shown. Mitochondria presented various morphological abnormalities such as outer membrane rupture (I; black arrow), loss of cristae (J), or multi-lammellar bodies (K; black arrowhead). G and H correspond to intact mitochondria completely (G) or partially (H) filled with cristae. Values are given as mean + SEM, n = 7 to 9 animals per group. ***p < 0.001, significance between CIH and NOX, ###p < 0.001, significance between WT and iNOS−/−

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Skeletal Muscle

ISSN: 2044-5040

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