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Fig. 5 | Skeletal Muscle

Fig. 5

From: The pan HDAC inhibitor Givinostat improves muscle function and histological parameters in two Duchenne muscular dystrophy murine models expressing different haplotypes of the LTBP4 gene

Fig. 5

Graph of the analysis of myofiber cross-sectional area (CSA) of muscles in mdx mice. Frequency graphs showing fiber CSA distributions in gastrocnemius (GAS) (A) and tibialis anterior (TA) (B) (5 mice/group, except for Naive wild type (wt) and Naive mdx groups, 4 mice/group). Each distribution was calculated as percentage of the total number of cases to account for the different number of cases within the groups. In Fig. 5A are also reported three examples of hematoxylin and eosin-stained transverse sections of myofibers areas in GAS of Naive WT, vehicle, and Givinostat 37.5 mg/kg treated mice

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Skeletal Muscle

ISSN: 2044-5040

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