Fig. 6
From: Mitochondrial dysfunction and consequences in calpain-3-deficient muscle
Myoblast proliferation behavior and effect of mitochondrial activity improvement on satellite cell markers. Proliferation kinetics of WT (Capn3+/+) and Capn3-deficient (Capn3−/−) myoblasts analyzed through flow cytometry by either CFSE fluorescence decrease (n = 4) (a) or manual counting (n = 5) (b). Expression of Pax7 mRNA (c) and MyoD mRNA (d) after 4 weeks of GW501516 treatment in the quadriceps muscle from 7-month-old Capn3−/− mice (n = 2). ***Significantly different with p < 0.001; *significantly different with p < 0.05