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Fig. 4 | Skeletal Muscle

Fig. 4

From: SMN-deficiency disrupts SERCA2 expression and intracellular Ca2+ signaling in cardiomyocytes from SMA mice and patient-derived iPSCs

Fig. 4

SERCA2a expression is reduced in SMA hearts. a qRT-PCR analysis of SERCA2 mRNA. Expression levels in SMN-deficient cardiomyocytes are represented relative to unaffected controls (n = 3). b Western blot analysis of SERCA2a protein levels. Quantification of SERCA protein level in SMA cells relative to controls at right. c qRT-PCR analysis of SERCA2a and SERCA2b mRNA. Expression levels in SMN-deficient (SMA) cardiomyocytes are represented relative to unaffected controls. Statistical analysis: p values shown for one-way ANOVA, Tukey’s post hoc test, n = 7

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Skeletal Muscle

ISSN: 2044-5040

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