Skip to main content
Fig. 4 | Skeletal Muscle

Fig. 4

From: Expressing a Z-disk nebulin fragment in nebulin-deficient mouse muscle: effects on muscle structure and function

Fig. 4

Ultrastructural analysis. a Representative images from skinned TC muscles for each treatment group. Z-disk misalignment (arrowheads) and rod bodies (arrows, insert) identified in AAV-treated CTRL mice. Black scale bar applicable to all images aside from the insert (white scale bar: 1000 nm). b Characterization of observed nemaline rod bodies. Left: rod body size, right: fractional area in muscle occupied by rod bodies. AAV treatment of Neb cKO mice reduces rod body size. Treatment in CTRL mice results in the formation of new rod bodies. (n = 103–191 rod bodies)

Back to article page

Skeletal Muscle

ISSN: 2044-5040

Contact us