Fig. 6

Effects of LARGE1 expression in Rh18 cells. a–c Western blotting of the parent cell line (Rh18) and Rh18 cells transduced with particles produced by an adenovirus encoding LARGE1 for matriglycan-modified α-dystroglycan (a), laminin-bound dystroglycan (b), and core α-dystroglycan (c). d Laminin binding to Rh18 cells and Rh18 cells infected with adenovirus-expressing LARGE1. Error bars, s.e.m.; n = 3, experimental replicate; **p < 0.01; ***p < 0.001; ****p < 0.0001