Skip to main content
Fig. 7 | Skeletal Muscle

Fig. 7

From: Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone

Fig. 7

Diaphragm tissue analysis from a 12-week exercised mdx study. a–c Representative images from the (top) vehicle control and (middle) 30 mg/kg FS-EEE-mFc and (bottom) total slide image analysis for a mouse IgG-positive staining for necrosis, b CD68-positive staining for macrophage infiltration, and c collagen I-positive staining for fibrosis. Note that due to high variability in IgG staining, total image analysis not shown for a. d qPCR of fibrosis and inflammation markers. *p < 0.05 compared to mdx vehicle-dosed group as described in the “Methods” section

Back to article page

Skeletal Muscle

ISSN: 2044-5040

Contact us