Group | A | B | C | D | |||||
---|---|---|---|---|---|---|---|---|---|
Timeline (months of age) | 1 | 2 | 1 | 2 | 3 | 4 | 5 | 6 | 9 |
Treadmill exercise (2×/week only P448Lneo− mice) | x | x | x | x | x | x | |||
Body weight | x | x | x | x | x | x | x | x | x |
Grip strength test | x | x | x | x | x | x | x | ||
Digiscan activity | x | x | x | x | x | x | x | ||
Echocardiography | x | x | x | ||||||
Plethysmography | x | x | x | ||||||
Serum creatinine kinase | x | x | x | x | |||||
Histology | x | x | x | x | |||||
Fibrosis | x | x | x | x |