Fig. 5
From: Role of Parkin and endurance training on mitochondrial turnover in skeletal muscle
Effect of Parkin and training on acute exercise performance. a Representative Western blot of Parkin localization on isolated mitochondria from untrained and trained WT muscle, prior to exercise (Con) and immediately following exercise (Ex). Quantification of mitochondrial Parkin localization is shown below, corrected for loading using mitochondrial voltage-dependent anion channel (VDAC) (n = 6, ¶P < 0.05, vs untrained Con). b Animal endurance performance (i.e. total distance run) of WT and KO animals (n = 8, *P < 0.05, main effect of training). c Blood lactate levels measured prior to (Con), and immediately following exercise (Ex) (n = 8, #P < 0.05, main effect of exercise). Values are means ± SEM. WT, wild type; KO, Parkin knockout; UT, untrained; T, trained; A.U., arbitrary units