Figure 5
From: Skeletal muscle laminin and MDC1A: pathogenesis and treatment strategies
A dy3K/ dy3Klaminin α2 chain-deficient mouse with a littermate (both 5 weeks old). Laminin α2 chain knockout mice have severe muscle wasting and growth retardation, resulting in dramatically decreased weight. Hind-limb paralysis (depicted with arrow), a result of peripheral neuropathy, is often seen before death.